Anorexia Nervosa

A Comprehensive Review of Complications and New Findings Associated with Anorexia Nervosa

Journal of Clinical Medicine
By Philip S. Mehler, MD, FACP, FAED, CEDS Leah Puckett, MD, MPH Daniela Grayeb, MD, FACP, CEDS Vishnupriya "Priya" Khatri, MD Kamila Cass, PhD, CEDS

Research Asset


Anorexia nervosa is a complex and deadly psychiatric disorder. It is characterized by a significant degree of both co-occurring psychiatric diseases and widespread physiological changes which affect nearly every organ system. It is important for clinicians to be aware of the varied consequences of this disorder. Given the high rate of mortality due to AN, there is a need for early recognition so that patients can be referred for appropriate medical and psychiatric care early in the course of the disorder. In this study, we present a comprehensive review of the recent literature describing medical findings commonly encountered in patients with AN. The varied and overlapping complications of AN affect pregnancy, psychological well-being, as well as bone, endocrine, gastrointestinal, cardiovascular, and pulmonary systems.

Written by

Philip S. Mehler, MD, FACP, FAED, CEDS

Dr. Philip S. Mehler began his career at Denver Health more than 35 years ago and was formerly its Chief of Internal Medicine and then Denver Health’s Chief Medical Officer (CMO) until he was promoted…
Written by

Leah Puckett, MD, MPH

Dr. Leah Puckett has been with ACUTE as a hospitalist since 2018. Dr. Puckett is also an Assistant Professor of Medicine at the University of Colorado School of Medicine. She completed her…
Written by

Vishnupriya "Priya" Khatri, MD

Dr. Priya Khatri joined the ACUTE Center for Eating Disorders & Severe Malnutrition in 2019 as a Hospitalist. Dr. Priya Khatri joined the ACUTE team in 2019. She finds working with a dedicated…
Written by

Kamila Cass, PhD, CEDS

Dr. Kamila Cass is a Clinical Psychologist at the ACUTE Center for Eating Disorders at Denver Health, providing psychodiagnostic assessment, individual and group psychotherapy, and crisis intervention…

ACUTE Earns Prestigious Center of Excellence Designation from Anthem
In 2018, the ACUTE Center for Eating Disorders & Severe Malnutrition at Denver Health was honored by Anthem Health as a Center of Excellence for Medical Treatment of Severe and Extreme Eating Disorders. ACUTE is the first medical unit ever to achieve this designation in the field of eating disorders. It comes after a rigorous review process.

Center of Excellence Logo